The player's vision is greatly impaired while damaged, similar to the health system in Gears of War. Rainbow Six Vegas changes the series with multiple new features, such as a new health system where the player regenerates health while not taking fire (the player may sometimes be killed instantly, without a chance to regenerate health this usually happens from grenades, as well as taking close-range fire from very powerful weapons, particularly to the head).

A sequel developed by Ubisoft Montreal was released on Xbox 360, and PlayStation 3 consoles in March 2008 and on PC in April 2008. The game's storyline follows a new team that is dispatched to Las Vegas, Nevada to defeat international terrorist Irena Morales and her army of mercenaries that are repeatedly attacking key locations in the city. The PlayStation Portable version was released on June 12, 2007, while the PlayStation 3 version was released on June 26, 2007. It was released for the Xbox 360 on November 21, 2006, and Windows on December 12, 2006.

Tom Clancy's Rainbow Six: Vegas is the sixth game in the Rainbow Six series of video games.

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